Fred W Perrino Selected Research

three prime repair exonuclease 1

10/2020	TREX1 - Apex predator of cytosolic DNA metabolism.
1/2020	T Cells Produce IFN-α in the TREX1 D18N Model of Lupus-like Autoimmunity.
1/2012	Defects in DNA degradation revealed in crystal structures of TREX1 exonuclease mutations linked to autoimmune disease.
9/2011	Dominant mutation of the TREX1 exonuclease gene in lupus and Aicardi-Goutieres syndrome.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Fred W Perrino Research Topics

Disease

8	Autoimmune Diseases (Autoimmune Disease) 01/2021 - 11/2008
7	Chilblain lupus 1 01/2019 - 05/2007
6	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2020 - 09/2007
3	Inflammation (Inflammations) 10/2020 - 12/2016
3	Aicardi-Goutieres syndrome 12/2011 - 05/2011
2	Bites and Stings (Sting) 01/2021 - 01/2020
1	Neoplasms (Cancer) 01/2021
1	Skin Diseases (Skin Disease) 12/2016
1	Psoriasis (Pustulosis Palmaris et Plantaris) 12/2016
1	Genomic Instability 01/2015
1	Arthralgia (Joint Pain) 05/2007
1	Werner Syndrome (Werner's Syndrome) 03/2007

Drug/Important Bio-Agent (IBA)

11	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 09/2007
5	Exonucleases (3' 5' Exonuclease)IBA 12/2016 - 03/2007
4	three prime repair exonuclease 1IBA 10/2020 - 09/2011
3	EnzymesIBA 10/2020 - 01/2015
3	Retinaldehyde (Retinal)IBA 01/2019 - 11/2008
2	Granzymes (Granzyme)IBA 09/2007 - 05/2007
1	Interferon Type IIBA 01/2021
1	Phosphodiesterase I (5' Exonuclease)IBA 01/2021
1	cyclic guanosine monophosphate-adenosine monophosphateIBA 01/2020
1	dolichyl-diphosphooligosaccharide - protein glycotransferase (oligosaccharyltransferase)IBA 07/2017
1	ChromatinIBA 12/2016
1	Imiquimod (Aldara)FDA LinkGeneric 12/2016
1	Nucleic AcidsIBA 04/2015
1	RibonucleotidesIBA 01/2015
1	Ribonuclease H (RNase H)IBA 01/2015
1	UbiquitinIBA 10/2013
1	AntibodiesIBA 01/2012
1	Interferon-alpha (Interferon Alfa)IBA 01/2012
1	deoxyguanosine triphosphate (dGTP)IBA 12/2011
1	Amino Acids FDA Link 09/2011
1	Ribonucleases (Ribonuclease)IBA 05/2011
1	3' Untranslated Regions (3' UTR)IBA 09/2007
1	Antinuclear AntibodiesIBA 05/2007
1	exodeoxyribonuclease IIBA 05/2007
1	CaspasesIBA 05/2007
1	Proteins (Proteins, Gene)FDA Link 03/2007
1	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 03/2007